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Goat Anti-Human CCR3

Chemokine receptors are G protein-coupled receptors (GPCRs) that play a key role in inflammation and are characterized by similar sequences with a 4 cysteine motif.  The C-C family has the first 2 cysteines linked together while the C-x-C family has an amino acid in between the first 2 cysteines.  Historically, this 355 amino acid chemokine receptor type 3 (CCR3) has been designated as C-C CKR-3, CC-CKR-3, CCR-3, CCR3, CKR3, Eosinophil eotaxin receptor, and CD193 antigen.

Specificity: Peptide sequence is < 50 % identical to other human chemokine receptors in this region.

Formulation: 200 µg per vial in 10 mM KHPO4, 140 mM NaCl with 1 mg/ml BSA and 0.1% sodium azide

Quality Control: Immunocytochemistry on human peripheral blood cells

Storage: Freeze at -20° C. For long term storage freeze at -70° C. Avoid freeze-thaw cycles.

capralogics

Immunocytochemistry on human peripheral blood cells

Contact Capralogics
antibodyinfo@capralogics.com
FAX 1-413-643-0067
Phone 1-800-975-6866

Product Number CIO119
Price $ 299
Amount 200 µg
Host Goat housed at Capralogics
Antigen

C-VETFGTTSYYDDVGLLCEKADTRALMA 28 amino acid synthetized corresponding to aa 8-34 (cysteine added for coupling) of the N-terminal domain of human CCR3
Purification Peptide affinity purified
Species Cross- Reactivity Not tested
Buffer 10 mM KHPO4, 140 mM NaCl
pH 7.2
*
Applications and Protocols  
ELISA (peptide) 1:60,000
Western Blotting

1:1,000
Immunohistochemistry (paraffin sections) 1:300
Immunocytochemistry (acetone fixed cells) 1:300

For Research Purposes Only
Citations and Applications
Johrer K, Zelle-Rieser C, Perathoner A, Moser P, Hager M, Ramoner R, Gander H, Holtl L, Bartsch G, Greil R, Thurnher M. Up-regulation of functional chemokine receptor CCR3 in human renal cell carcinoma.  Clin Cancer Res. 2005 Apr 1;11(7):2459-65. Full Text IH

Capralogics Home >> Chemokine Receptor Index