capralogics inc

Mouse CCR9 External Cellular Domain

Historically, chemokine receptor C-C chemokine receptor type 9 (CCR9) has been designated as C-C chemokine receptor type 9 (C-C CKR-9), CC-CKR-9, CCR-9, GPR-9-6, G-protein coupled receptor 28, and CDw199 antigen

Specificity: Peptide sequence is < 50 % identical to other mouse chemokine receptors in this peptide region. The antibody recognizes mouse CCR9 and cross-reacts to human CCR9 due to 76 % homology within this peptide region.

Formulation: Liquid 200 µg of peptide affinity purified IgG antibody in 10 mM KHPO4, 140 mM NaCl with 1 mg/ml BSA and 0.1 % sodium azide

Quality Control: Immunohistochemistry on mouse spleen

Storage: Freeze at -20° C. For long term storage freeze at -70° C. Avoid freeze-thaw cycles.

capralogics anti CCR9

Above: IH paraffin section mouse spleen ENLARGE

For Research Purposes Only
Contact Capralogics antibodyinfo@capralogics.com
FAX 1-413-643-0067
Phone 1-800-975-6866

Product Number CIO125
Price $ 299
Amount 200 µg
Host Goat housed at Capralogics
Antigen

Synthetic peptide IPGMFDDFSYDSTASTDDYMNLNFSSFF corresponding to amino acids 10-37 of mouse CCR9
Purification Peptide affinity purified
Species Cross- Reactivity Human
Buffer 10 mM KHPO4, 140 mM NaCl
pH 7.2
*
Applications and Protocols  
ELISA (peptide) 1:100,000
Western Blotting - WB

1:1,000
Immunocytochemistry - IC 1:250
Immunohistochemistry - IH 1:250
Flow Cytometry - FC 1:200
Citations and Applications
Marski M, Ye AL, Abraham C. CD18 is required for intestinal T cell responses at multiple immune checkpoints.  J Immunol. 2007 Feb 15;178(4):2104-12.  Abstract FC
Liu JX, Cao X, Tang YC, Liu Y, Tang FR.  CCR7, CCR8, CCR9 and CCR10 in the mouse hippocampal CA1 area and the dentate gyrus during and after pilocarpine-induced status epilepticus.  Neurochem 2007 Feb;100(4):1072-88.  Abstract IC
Note: This product is likely to be neutralizing because the antibody to similiar domains of human CCR9 block TECK induced activation of ES-2 cells.

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