|
|||||||||||||||||||||||||||||||
|
Specificity: Peptide sequence is < 50 % identical to other human chemokine receptors in this region. The antibody recognizes human CCR10 and was not tested for cross-reactivity to mouse CCR10. Formulation: Liquid 200 µg of peptide affinity purified IgG antibody in 10 mM KHPO4, 140 mM NaCl with 1 mg/ml BSA and 0.1 % sodium azide Quality Control: Immunohistochemistry on human spleen Storage: Freeze at -20° C. For long term storage freeze at -70° C. Avoid freeze-thaw cycles.
Above: IH paraffin section of human spleen ENLARGE For Research Purposes Only |
Above: IH paraffin section of human tonsil ENLARGE |
||||||||||||||||||||||||||||||
Citations and Applications |
| Castelletti E, Lo Caputo S, Kuhn L, Borelli M, Gajardo J, Sinkala M, Trabattoni D, Kankasa C, Lauri E, Clivio A, Piacentini L, Bray DH, Aldrovandi GM, Thea DM, Veas F, Nebuloni M, Mazzotta F, Clerici M. The Mucosae-Associated Epithelial Chemokine (MEC/CCL28) Modulates Immunity in HIV Infection. PLoS ONE. 2007 Oct 3;2(10):e969. Full Text FC |
| Eksteen B, Miles A, Curbishley SM, Tselepis C, Grant AJ, Walker LS, Adams DH. Epithelial inflammation is associated with CCL28 production and the recruitment of regulatory T cells expressing CCR10. J Immunol. 2006 Jul 1;177(1):593-603. Full Text FC |
| Luttichaux IV, Notohamiprodjo M, Wechselberger A, Peters C, Henger A, Seliger C, Djafarzadeh R, Huss R, Nelson PJ. Human Adult CD34() Progenitor Cells Functionally Express the Chemokine Receptors CCR1, CCR4, CCR7, CXCR5, and CCR10 but Not CXCR4. Stem Cells Dev 2005 Jun;14(3):329-36 Abstract FC |
| Notohamiprodjo M, Segerer S, Huss R, Hildebrandt B, Soler D, Djafarzadeh R, Buck W, Nelson PJ, von Luettichau I. CCR10 is expressed in cutaneous T-cell lymphoma. Int J Cancer. 2005 Jul 1;115(4):641-7. Abstract FC |
| Hislop AD, Kuo M, Drake-Lee AB, Akbar AN, Bergler W, Hammerschmitt N, Khan N, Palendira U, Leese AM, Timms JM, Bell AI, Buckley CD, Rickinson AB. Tonsillar homing of Epstein-Barr virus-specific CD8+ T cells and the virus-host balance. J Clin Invest. 2005 Sep;115(9):2546-55. Full Text FC |
| Hirata T, Furukawa Y, Yang BG, Hieshima K, Fukuda M, Kannagi R, Yoshie O, Miyasaka M. Human P-selectin glycoprotein ligand-1 (PSGL-1) interacts with the skin-associated chemokine CCL27 via sulfated tyrosines at the PSGL-1 amino terminus. J Biol Chem. 2004 Dec 10;279(50):51775-82. Full Text FC |
| Murakami T, Cardones AR, Finkelstein SE, Restifo NP, Klaunberg BA, Nestle FO, Castillo SS, Dennis PA, Hwang ST. Immune evasion by murine melanoma mediated through CC chemokine receptor-10. J Exp Med. 2003 Nov 3;198(9):1337-47. Full text IH, WB |
