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Antibody to IL-23 receptor

DATASHEET
Specificity: This antibody recognizes both human and mouse IL-23 receptor

Formulation: Liquid 200 µg of affinity purified antibody in 10 mM KHPO4, 140 mM NaCl with 0.1 % sodium azide and 1 mg/ml BSA

Quality Control: Immunohistochemistry on paraffin sections of human and mouse spleens

Storage: Freeze at -20 °C or colder. Stable for at least 3 years when stored at -80°C. Avoid freeze/thaw cycles.

Capralogics anti-IL23R

Above: IH of CI0157 antibody to IL-23 receptor on paraffin section of human spleen

Capralogics anti-IL23R

Above: IH of CI0157 antibody to IL-23 receptor on paraffin section of mouse spleen
Contact Capralogics
antibodyinfo@capralogics.com
FAX 1-413-643-0067
Phone 1-800-975-6866

Product Number CIO157
Price $ 295
Amount 200 µg in 100 µl
Host Goat
Antigen Synthetic peptide CQPRKLHFYKNGIKERFQITRINKTTARL corresponding to amino acids 59-87 of the N-terminal domain of human IL-23 receptor
Sequence Human IL-23 receptor
CQPRKLHFYKNGIKERFQITRINKTTARL    +PR+ L+FYKNG+KE+F+ITRIN+TTAR+
CRPRNLYFYKNGFKEEFDITRINRTTARI 
Mouse IL-23 receptor
Antibody Concentration

2.0 mg/mL
Purification Peptide affinity purified
Species Cross- Reactivity mouse
Buffer 10 mM KHPO4, 140 mM NaCl
pH 7.2
Applications and Protocols  
Western Blot (WB) 1:1000
Immunocytochemistry (IC) on acetone fixed cells 1:400
Immunohistochemistry (IH) on paraffin sections 1:250
Flow Cytometry (FC) ND

Link to larger immunohistochemistry images

 

For Research Purposes Only
Reference
Parham C, Chirica M, Timans J, Vaisberg E, Travis M, Cheung J, Pflanz S, Zhang R, Singh KP, Vega F, To W, Wagner J, O'Farrell AM, McClanahan T, Zurawski S, Hannum C, Gorman D, Rennick DM, Kastelein RA, de Waal Malefyt R, Moore KW.  A receptor for the heterodimeric cytokine IL-23 is composed of IL-12Rbeta1 and a novel cytokine receptor subunit, IL-23R.  J Immunol. 2002 Jun 1;168(11):5699-708.   Full Text

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