Capralogics, Inc., P.O. Box 356, Hardwick, MA 01037 USA
Phone (800) 975-6866 / (413) 477-6866 • FAX (413) 643-0067 • capralogics.com

anti-Adiponectin Receptor AdipoR2 N-terminus

$295.00
SKU: CI0165

CI0165: Adiponectin Receptor 2 N term. IH Paraffin human muscle (above)

Specifications

Amount: 
200 ug
Host Species: 
Goat
Antigen: 
30 amino acid (aa) synthetic peptide CSRTPEPDIRLRKGHQLDGTRRGDNDSHQG corresponding to aa 11-40 of the N-terminal domain of human AdipoR2
Reactive Species: 
Human
Mouse
Format/Conjugates/Purification: 
Peptide Affinity Purification
Buffer & Formulation: 
Affinity purified antibody in 10 mM KHPO4, 140 mM NaCl, BSA @ 1mg/ml and 0.1 % sodium azide
Storage: 
Aliquot and freeze at -20° C. Avoid freeze-thaw cycles.
Clone: 
Polyclonal

Applications

Western Blotting: 
1:1000
IHC: 
1:250 (paraffin sections)
Comments: 

Adiponectin receptor 2 (AdipoR2) is an integral membrane protein with seven transmembrane domains with an internal N-terminus and an external C-terminus. AdipoR2 is highly conserved among species and expressed mainly in the liver and skeletal muscle. Expression of AdipoR2 in the brain correlates with brain development and size in mice.

References: 

Bjursell M, Ahnmark A, Bohlooly-Y M, William-Olsson L, Rhedin M, Peng XR, Ploj K, Gerdin AK, Arnerup G, Elmgren A, Berg AL, Oscarsson J, Lindén D. Opposing effects of adiponectin receptors 1 and 2 on energy metabolism.  Diabetes. 2007 Mar;56(3):583-93.  Full Text
Kadowaki T, Yamauchi T, Kubota N, Hara K, Ueki K, Tobe K. Adiponectin and adiponectin receptors in insulin resistance, diabetes, and the metabolic syndrome.  J Clin Invest. 2006 Jul;116(7):1784-92. Full Text
Rasmussen MS, Lihn AS, Pedersen SB, Bruun JM, Rasmussen M, Richelsen B.  Adiponectin receptors in human adipose tissue: effects of obesity, weight loss, and fat depots.  Obesity (Silver Spring). 2006 Jan;14(1):28-35. Full Text
Staiger H, Kaltenbach S, Staiger K, Stefan N, Fritsche A, Guirguis A, Peterfi C, Weisser M, Machicao F, Stumvoll M, Haring HU.   Expression of adiponectin receptor mRNA in human skeletal muscle cells is related to in vivo parameters of glucose and lipid metabolism.  Diabetes. 2004 Sep;53(9):2195-201. Full Text
Yamauchi T, et al. Cloning of adiponectin receptors that mediate antidiabetic metabolic effects.  Nature. 2003 Jun 12;423(6941):762-9.  Abstract

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