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DATASHEET Description: The immunogen prepared for sheep housed at Capralogics was intact calf histone H1 at 21 kD, 194 amino acids, complexed with RNA. Calf histone H1 has > 90% identity to other mammalian histone H1 proteins. Cross-Reactivity: None with histone core proteins H2A, H2B, H3 or H4. Product: Protein G purified immunoglobulin in phosphate buffered saline, pH 7.4. Large volumes of antisera to Histone H1 available for sale. Storage: Aliquot and store at -20° C or store at 4° C with the addition of 0.1% sodium azide. Avoid repeated freeze-thaw cycles. Related Products: Antibodies to histone core, histone H2B, and histone H3 For Research Purposes Only |
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Citations and Applications |
| Muir C, Chung LW, Carson DD, Farach-Carson MC. Hypoxia increases VEGF-A production by prostate cancer and bone marrow stromal cells and initiates paracrine activation of bone marrow endothelial cells. Clin Exp Metastasis. 2006;23(1):75-86. Abstract WB |
| Zhu G, Chen H, Choi BK, Del Piero F, Schifferli DM. Histone H1 proteins act as receptors for the 987P fimbriae of enterotoxigenic Escherichia coli. J Biol Chem. 2005 Jun 17;280(24):23057-65. Full Text WB |
| Wondrak GT, Cervantes-Laurean D, Jacobson EL, Jacobson MK. Histone carbonylation in vivo and in vitro. Biochem J. 2000 Nov 1;351 Pt 3:769-77. Full Text WB |
| Brix K, Summa W, Lottspeich F, Herzog V. Extracellularly occurring histone H1 mediates the binding of thyroglobulin to the cell surface of mouse macrophages. J Clin Invest. 1998 Jul 15;102(2):283-93. Full Text IF |
