Capralogics, Inc., P.O. Box 356, Hardwick, MA 01037 USA
Phone (800) 975-6866 / (413) 477-6866 • FAX (413) 643-0067 • capralogics.com

Beta Chemokine Receptor D6 (human) Biotin Conjugated IgG

$299.00
SKU: CI0171
Synonyms: 
CCR D6; D6; Beta Chemokine Receptor D6

CI0171: Immunohistochemistry with CCR D6 Biotin Conjugate antibody to human Chemokine Receptor D6 on paraffin sections of human spleen.

Specifications

Amount: 
100 ug
Host Species: 
Goat
Antigen: 
Synthetic peptide C-LATEDADSENSSFYYYDYLDEVAFML corresponding to the N-terminal extracellular domain of human D6
Reactive Species: 
Human
Format/Conjugates/Purification: 
Peptide Affinity Purification
Buffer & Formulation: 
10 mM KHPO4, 140 mM NaCl, BSA @ 1mg/ml and 0.1 % sodium azide. pH 7.2
Storage: 
Aliquot and freeze at -80° C. Stable for 3 years when stored at -80C. Avoid freeze-thaw cycles.
Clone: 
Polyclonal

Applications

ELISA: 
1:100000
Western Blotting: 
2 ug/ml
IHC: 
8 ug/ml
Comments: 

Peptide sequence is < 50 % identical to other chemokine receptors in this region and cross-reactivity to mouse D6 was not tested.

Unconjugated version of this antibody is acceptable for Flow Cytometry.

Quality Control:  Immunohistochemistry on human spleen.

References: 

Neil SJ, Aasa-Chapman MM, Clapham PR, Nibbs RJ, McKnight A, Weiss RA.  The promiscuous CC chemokine receptor D6 is a functional coreceptor for primary isolates of human immunodeficiency virus type 1 (HIV-1) and HIV-2 on astrocytes.  J Virol.  2005 Aug;79(15):9618-24.  Full Text FC

Nibbs RJB et al.  Cloning and characterzation of a novel promiscuous human beta-chemokine receptor D6  J Biol. Chem. 1997, vol 272: 32078-83

Questions?
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info@capralogics.com

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