Capralogics, Inc., P.O. Box 356, Hardwick, MA 01037 USA
Phone (800) 975-6866 / (413) 477-6866 • FAX (413) 643-0067 • capralogics.com
Phone (800) 975-6866 / (413) 477-6866 • FAX (413) 643-0067 • capralogics.com
Beta Chemokine Receptor D6 (human) Biotin Conjugated IgG
$325.00
Specifications
Amount:
100 ug
Host Species:
Goat
Antigen:
Synthetic peptide C-LATEDADSENSSFYYYDYLDEVAFML corresponding to the N-terminal extracellular domain of human D6
Reactive Species:
Human
Format/Conjugates/Purification:
Peptide Affinity Purification
Buffer & Formulation:
10 mM KHPO4, 140 mM NaCl, BSA @ 1mg/ml and 0.1 % sodium azide. pH 7.2
Storage:
Aliquot and freeze at -80° C. Stable for 3 years when stored at -80C. Avoid freeze-thaw cycles.
Clone:
Polyclonal
Applications
ELISA:
1:100000
Western Blotting:
2 ug/ml
IHC:
8 ug/ml
Comments:
Peptide sequence is < 50 % identical to other chemokine receptors in this region and cross-reactivity to mouse D6 was not tested.
Unconjugated version of this antibody is acceptable for Flow Cytometry.
Quality Control: Immunohistochemistry on human spleen.
References:
Neil SJ, Aasa-Chapman MM, Clapham PR, Nibbs RJ, McKnight A, Weiss RA. The promiscuous CC chemokine receptor D6 is a functional coreceptor for primary isolates of human immunodeficiency virus type 1 (HIV-1) and HIV-2 on astrocytes. J Virol. 2005 Aug;79(15):9618-24. Full Text FC
Nibbs RJB et al. Cloning and characterzation of a novel promiscuous human beta-chemokine receptor D6 J Biol. Chem. 1997, vol 272: 32078-83